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five prime untranslated region
The 5' untranslated region (5′ UTR) (also known as a ''Leader Sequence'' or ''Leader RNA'') is the region of an mRNA that is directly upstream from the initiation codon. This region is important for the regulation of translation of a transcript by differing mechanisms in viruses, prokaryotes and eukaryotes. While called untranslated, the 5′ UTR or a portion of it is sometimes translated into a protein product. This product can then regulate the translation of the main coding sequence of the mRNA. In many other organisms, however, the 5′ UTR is completely untranslated, instead forming complex secondary structure to regulate translation. The 5′ UTR has been found to interact with proteins relating to metabolism; and proteins translate sequences within the 5′ UTR. In addition, this region has been involved in transcription regulation, such as the sex-lethal gene in Drosophila.〔 Regulatory elements within 5' UTRs have also been linked to mRNA export.
== General structure ==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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